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Astaxanthin Activates the FOX03 'Longevity Gene'

Posted on March 29, 2017, 6 a.m. in Longevity Anti-Aging Research Science Genetic Research

The Astaxanthin compound CDX-085, developed by Cardax, shows the ability to markedly increase the expression of the FOXO3 gene in a lab animal model.

An Astaxanthin compound known as CDX-085 has displayed the ability to boost the expression of FOX03, a gene that is pivotal to longevity. At the moment, studies have been limited to mice. The research was reported by Cardax, a life sciences company, and academicians from the University of Hawaii's John A. Burns School of Medicine. The hope is that these findings will lead to a highly effective anti-aging therapy that extends the lifespan of human beings.

A Brief Description of Astaxanthin


Astaxanthin
is a compound that naturally occurs in seafood like salmon and shrimp. It is commonly obtained from algae and krill. Numerous studies performed on animals show that Astaxanthin minimizes inflammation as well as damage to the liver and the heart. Astaxanthin even reduces the odds of a stroke and lowers cholesterol levels. Though extensive Astaxanthin research has not been conducted on humans, it is known that the compound decreases triglycerides and inflammation.

Astaxanthin is used as an active ingredient in a compound patented by Cardax known as CDX-085. This compound sends Astaxanthin into the blood stream, allowing for deep absorption. Studies performed on animals show that CDX-085 reduces triglycerides, blood clots and atherosclerosis by more than 70 percent.

About the Research

Every human being has the FOX03 gene that guards against aging. However, one in three individuals has a version of the gene that is tied to longevity. If the gene is activated in all humans, it can function like the longevity version. The above-referenced scientists have found that Astaxanthin activates the gene.

The study was the first of its kind to determine the potential of Astaxanthin to activate FOX03. Some of the study's mice were fed high and low doses of Astaxanthin CDX-085 while others were fed regular food. Those fed significant amounts of Astaxanthin CDX-085 enjoyed a large bump (90 percent) in the activation of the FOX03 within their heart tissue.

Why the Research Matters


This study is acclaimed as groundbreaking as it lends support to the notion that Astaxanthin can combat the aging process and prolong human lives. It is also interesting to note that the research was performed in unison between a publicly funded academic institution and a private company. This is an example of the type of teamwork between government and private industry that will be necessary to advance the human condition across posterity.

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